Robert J. Robbins Johns Hopkins University rrobbins@gdb.org
cross-file: N_drive:jhuclass1995mol-bio.ppt
© 1994, 1995 Robert Robbins
Molecular Biology: 1
Origins of Molecular Biology
Phenotype
holy Genetics
(1900s)
Biochemistry
(1900s)
Genes
Proteins
?
The phenotype of an organism denotes its external appearance (size, color, intelligence, etc.). Classical genetics showed that genes control the transmission of phenotype from nonpareil generation to the next. Biochemistry showed that at bottom one generation, proteins had a determining effect on phenotype. For galore(postnominal) years, however, the relationship between genes and proteins was a mystery. Then, it was found that genes contain digitally encoded instructions that direct the synthesis of proteins. The crucial insight of molecular(a) biology is that hereditary information is passed between generations in a form that is truly, not metaphorically, digital. Understanding how that digital code directs the concept of life is the goal of molecular biology.
Phenotype
Classical Genetics
(1900s)
Biochemistry
(1900s)
Genes
Molecular Biology
show: N_drive:jhuclass1995mol-bio.
ppt © 1994, 1995 Robert Robbins
Proteins
Molecular Biology: 2
Classical Genetics
(1900s)
Phenotype
Classical Genetics
Genes
Proteins
CC C C
P
c
cc c
Cc
F1
C c c C c C
Cc
C
c
CC
Cc
F2
Cc
cc
Regular numerical patterns of inheritance showed that the passage of traits from one generation to the next could be explained with the assumption that hypothetical particles, or genes, were carried in pairs in adults, but transmitted individually to progeny.
File: N_drive:jhuclass1995mol-bio.ppt
© 1994, 1995 Robert Robbins
Molecular Biology: 3
Classical Genetics
During the first fractional of this century, classical investigation of the gene established that theoretical objects called genes were the fundamental units of...If you want to get a full essay, order it on our website: Ordercustompaper.com
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